Llano is an unincorporated community located about 25 miles southeast of Palmdale in the Antelope Valley. The town of Pearblossom lies to the west while the town of Pinon Hills lies to the east. Pearblossom Highway (State Route 138) runs through the heart of Llano and is its principal street. Vacant land and residential properties in this area are serviced by several water districts and septic systems.

The region experiences warm, but not hot, dry summers with no average monthly temperature above 71 degrees. Llano was once the home of English writer Aldous Huxley. At the turn of the 20th century there was a socialist colony in Llano. The ruins of Llano Del Rio still exist along Highway 138 east of 165th Street East.